| Primary Identifier | MGI:2152895 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 117599 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA helicase activity. Involved in DNA damage response; negative regulation of double-strand break repair via homologous recombination; and regulation of DNA double-strand break processing. Acts upstream of or within DNA-templated DNA replication. Located in cytoplasm and nucleus. Orthologous to human HELB (DNA helicase B). PHENOTYPE: Homozygous knockout MEFs display increased DNA end resection, resulting in increased level of single-strand DNA formation at double-strand DNA breaks. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
