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Protein Coding Gene : Lrig3 leucine-rich repeats and immunoglobulin-like domains 3
Primary Identifier  MGI:2443955 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  320398
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Acts upstream of or within otolith morphogenesis. Predicted to be located in cytoplasmic vesicle membrane and plasma membrane. Is expressed in several structures, including branchial arch; embryo mesenchyme; nervous system; pancreas tip epithelium; and sensory organ. Orthologous to human LRIG3 (leucine rich repeats and immunoglobulin like domains 3).
PHENOTYPE: Mice homozygous for a null allele or severely hypomorphic gene trap allele exhibit fusion of the lateral semicircular canal and circling behavior. [provided by MGI curators]
  • synonyms:
  • mKIAA3016,
  • RIKEN cDNA 9030421L11 gene,
  • 9130004I02Rik,
  • MGI:1926172,
  • leucine-rich repeats and immunoglobulin-like domains 3,
  • RIKEN cDNA 9130004I02 gene,
  • 9430095K15Rik,
  • RIKEN cDNA 9430095K15 gene,
  • MGI:1914812,
  • Lrig3,
  • 9030421L11Rik
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