Primary Identifier | MGI:104539 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 103161 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within cholesterol efflux; cholesterol metabolic process; and triglyceride metabolic process. Predicted to be part of high-density lipoprotein particle and low-density lipoprotein particle. Predicted to be active in extracellular space. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system gland; and liver. Orthologous to human APOF (apolipoprotein F). PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired ABCG1-mediated cholesterol efflux. [provided by MGI curators] |