Primary Identifier | MGI:2143670 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 103284 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable miRNA binding activity. Predicted to be involved in negative regulation of miRNA processing and regulation of RNA splicing. Predicted to act upstream of with a positive effect on post-transcriptional regulation of gene expression. Predicted to be located in nucleus. Is expressed in early conceptus; inner cell mass; and oocyte. Orthologous to human ZC3H10 (zinc finger CCCH-type containing 10). PHENOTYPE: Mice with loss of expression in adipose tissue display impaired adaptive thermogenesis, increased body weight, impaired glucose tolerance, and impaired insulin sensitivity. [provided by MGI curators] |