Primary Identifier | MGI:1915065 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 67815 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable enzyme activator activity and transferase activity, transferring alkyl or aryl (other than methyl) groups. Predicted to be involved in positive regulation of cholesterol biosynthetic process. Predicted to be located in nucleoplasm. Predicted to be active in cytosol. Is expressed in 1st branchial arch maxillary component; nasal pit; otocyst; and trunk somite. Orthologous to human SEC14L2 (SEC14 like lipid binding 2). PHENOTYPE: Mice homozygous for a null allele exhibit decreased cholesterol synthesis and plasma levels under fasting conditions compared to wild-type mice. [provided by MGI curators] |