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Protein Coding Gene : Kremen1 kringle containing transmembrane protein 1

Primary Identifier  MGI:1933988 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  84035
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable transmembrane signaling receptor activity. Involved in several processes, including negative regulation of axon regeneration; negative regulation of canonical Wnt signaling pathway; and negative regulation of ossification. Located in neuronal cell body. Is expressed in several structures, including alimentary system; brain; genitourinary system; limb ectoderm; and sensory organ. Human ortholog(s) of this gene implicated in ectodermal dysplasia 13. Orthologous to human KREMEN1 (kringle containing transmembrane protein 1).
PHENOTYPE: Mice homozygous for a null allele exhibit no abnormal phenotype. [provided by MGI curators]
  • synonyms:
  • kringle containing transmembrane protein 1,
  • expressed sequence AV002070,
  • Kremen1,
  • MGI:2144448,
  • AV002070,
  • Krm1

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

1 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For