| Primary Identifier | MGI:1927091 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 246177 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables phosphatidylinositol-3,4,5-trisphosphate binding activity; phosphatidylinositol-3,4-bisphosphate binding activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in Fc-gamma receptor signaling pathway involved in phagocytosis and T cell mediated immunity. Acts upstream of or within several processes, including T cell meandering migration; cell gliding; and phagocytosis. Located in several cellular components, including lamellipodium; microvillus; and phagocytic cup. Orthologous to human MYO1G (myosin IG). PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced B cell spreading, migration and homing and impaired T cell motility. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
