Primary Identifier | MGI:1202066 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 20335 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein transmembrane transporter activity and ribosome binding activity. Predicted to be involved in post-translational protein targeting to membrane, translocation. Predicted to be located in membrane. Predicted to be part of Ssh1 translocon complex. Is expressed in lung epithelium; ovary; and seminiferous cord. Orthologous to human SEC61G (SEC61 translocon subunit gamma). PHENOTYPE: Mice homozygous for a knock-out allele show complete embryonic lethality prior to organogenesis. In vitro, blastocysts fail to hatch from the zona pellucida and die after 3 days in culture. [provided by MGI curators] |