| Primary Identifier | MGI:1860485 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 56193 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable phosphatidylinositol-3,4-bisphosphate binding activity; protein homodimerization activity; and protein kinase C binding activity. Involved in several processes, including G protein-coupled receptor signaling pathway; exocytosis; and positive regulation of cellular component organization. Predicted to be located in cytoplasm and ruffle membrane. Predicted to be active in plasma membrane. Orthologous to human PLEK (pleckstrin). PHENOTYPE: Mice homozygous for a null mutation display mild thrombocytopenia, impaired platelet aggregation, and impaired platelet granule secretion. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
