| Primary Identifier | MGI:2667252 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 216565 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Predicted to enable actin filament binding activity and small GTPase binding activity. Predicted to be involved in actin cytoskeleton organization and endocytic recycling. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in plasma membrane. Is expressed in brain. Orthologous to human EHBP1 (EH domain binding protein 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased embryo size, incomplete embryo turning, abnormal head and heart shape, abnormal fore- and midbrain morphology, branchial arch defects, pale yolk sacs, caudal neural tube kinks, abnormal tails, placentation defects, and complete lethality during organogenesis. A minority exhibit incomplete closure of the cranial neural tube. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
