| Primary Identifier | MGI:2441843 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 237716 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables C-C chemokine receptor activity. Involved in chemokine-mediated signaling pathway. Predicted to be active in plasma membrane. Is expressed in several structures, including heart; liver; metanephros; skeletal muscle; and spleen. Orthologous to human GPR75 (G protein-coupled receptor 75). PHENOTYPE: Mice homozygous for a knock-out allele exhibit a mild progressive retinal degeneration caused by loss of both M-cone and S-cone photoreceptor cells that is accompanied by oxidative stress. Another null allele shows increased anxiety-like behaviors and disrupted fear conditioning recall. Males are resistant age-related gain in body mass. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
