Primary Identifier | MGI:1917607 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 70357 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable calcium ion binding activity; potassium channel regulator activity; and transmembrane transporter binding activity. Predicted to be involved in positive regulation of action potential; regulation of potassium ion transmembrane transport; and regulation of signal transduction. Part of voltage-gated potassium channel complex. Is expressed in several structures, including brain; ganglia; intestine smooth muscle circular layer; spinal cord; and testis. Orthologous to human KCNIP1 (potassium voltage-gated channel interacting protein 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increase susceptibility to pentylenetetrazole-induced seizures. [provided by MGI curators] |