Primary Identifier | MGI:2388637 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 211652 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable kinase binding activity; signaling adaptor activity; and transcription coactivator activity. Predicted to be involved in several processes, including hippo signaling; negative regulation of organ growth; and regulation of intracellular signal transduction. Located in cytoplasm. Is expressed in cerebral cortex; female associated reproductive structure; forelimb bud ectoderm; primitive collecting duct; and retina. Orthologous to human WWC1 (WW and C2 domain containing 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired adult synaptic plasticity and fear-based conditioning. [provided by MGI curators] |