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Protein Coding Gene : Adam19 ADAM metallopeptidase domain 19
Primary Identifier  MGI:105377 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  11492
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables SH3 domain binding activity. Acts upstream of or within heart development and membrane protein ectodomain proteolysis. Located in Golgi apparatus. Is expressed in several structures, including central nervous system; genitourinary system; heart; limb; and trunk. Orthologous to human ADAM19 (ADAM metallopeptidase domain 19).
PHENOTYPE: Homozygous null mice exhibit cardiac developmental defects and die perinatally. [provided by MGI curators]
  • synonyms:
  • MGI:2144353,
  • expressed sequence AL024287,
  • Adam19,
  • ADAM metallopeptidase domain 19,
  • meltrin, beta,
  • AL024287,
  • Mltnb,
  • MGD-MRK-33046
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Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

Trail: ProteinCodingGene

0 Strain

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

10 Pathways

Trail: ProteinCodingGene

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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