| Primary Identifier | MGI:1891717 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 59044 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ubiquitin protein ligase activity. Involved in programmed cell death. Predicted to be located in membrane. Predicted to be active in cytoplasm. Is expressed in several structures, including central nervous system; male reproductive system; retina; and urinary system. Orthologous to human RNF130 (ring finger protein 130). PHENOTYPE: Mice homozygous for a hypomorphic allele show partial prenatal lethality, increased hepatic low-density lipoprotein receptor (LDLR) protein levels, and decreased plasma LDL cholesterol (LDL-C) levels. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
