| Primary Identifier | MGI:1924151 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 76901 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ubiquitin protein ligase activity. Acts upstream of or within neuron projection extension; positive regulation of neurogenesis; and protein ubiquitination. Predicted to be located in nucleoplasm. Predicted to be part of histone acetyltransferase complex. Is expressed in central nervous system and genitourinary system. Orthologous to human JADE2 (jade family PHD finger 2). PHENOTYPE: Homozygous null mice show impaired basal synaptic transmission and synaptic plasticity in the hippocampus with decreased dendritic spine density, and impaired object recognition and spatial reference memory. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
