Primary Identifier | MGI:2685369 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 245827 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable calcium ion binding activity. Predicted to be involved in cell-substrate adhesion; epithelial cell migration; and homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to be located in Golgi apparatus and plasma membrane. Predicted to be active in adherens junction. Is expressed in several structures, including alimentary system; brain; hemolymphoid system gland; nose; and urinary system. Human ortholog(s) of this gene implicated in spinocerebellar ataxia 45. Orthologous to human FAT2 (FAT atypical cadherin 2). PHENOTYPE: Mice homozygous for a knock-out allele are healthy, fertile and overtly normal, with no apparent defects in the development of red blood cells or platelets. [provided by MGI curators] |