Primary Identifier | MGI:1922679 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 75429 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable microtubule binding activity. Involved in flagellated sperm motility. Located in centrosome and ciliary basal body. Is active in axonemal B tubule inner sheath; ciliary base; and sperm flagellum. Is expressed in several structures, including brain ventricle and choroid plexus; gonad; notochord; respiratory system; and sensory organ. Orthologous to several human genes including CFAP144 (cilia and flagella associated protein 144). PHENOTYPE: Mice homozygous for a knock-out allele are viable and fertile and do not display any defects indicative of motile ciliary dysfunction. [provided by MGI curators] |