Primary Identifier | MGI:99431 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 11840 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables GTP binding activity and magnesium ion binding activity. Involved in mitotic cleavage furrow ingression. Acts upstream of or within vesicle-mediated transport. Located in Golgi apparatus; cytosol; and sarcomere. Part of protein-containing complex. Is expressed in several structures, including brain; genitourinary system; gut; hemolymphoid system; and integumental system. Human ortholog(s) of this gene implicated in periventricular nodular heterotopia. Orthologous to human ARF1 (ARF GTPase 1). PHENOTYPE: Homozygous embryos die in utero shortly after implantation. [provided by MGI curators] |