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Protein Coding Gene : Alkbh5 alkB homolog 5, RNA demethylase

Primary Identifier  MGI:2144489 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  268420
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables mRNA N6-methyladenosine dioxygenase activity. Involved in mRNA destabilization and spermatogenesis. Located in nuclear speck. Is expressed in brain; intestine; and liver. Orthologous to human ALKBH5 (alkB homolog 5, RNA demethylase).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced male fertility associated with oligo- and teratozoopermia and male germ cell apoptosis. [provided by MGI curators]
  • synonyms:
  • oxoglutarate and iron-dependent oxygenase domain containing,
  • MGI:2144515,
  • AW215868,
  • expressed sequence AW050020,
  • expressed sequence AW215868,
  • AW050020,
  • Alkbh5,
  • Abh5,
  • alkB homolog 5, RNA demethylase,
  • Ofoxd

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

1 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For