Primary Identifier | MGI:108495 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 16515 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable PDZ domain binding activity and inward rectifier potassium channel activity. Predicted to be involved in potassium ion import across plasma membrane; protein homotetramerization; and regulation of monoatomic ion transmembrane transport. Predicted to be located in T-tubule; dendrite; and neuronal cell body. Predicted to be part of monoatomic ion channel complex. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and integumental system. Orthologous to several human genes including KCNJ12 (potassium inwardly rectifying channel subfamily J member 12). PHENOTYPE: Homozygotes for a targeted null mutation are viable and fertile with no detected abnormalities. [provided by MGI curators] |