Primary Identifier | MGI:1926089 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 109342 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables fructose:sodium symporter activity and mannose:sodium symporter activity. Predicted to be involved in fructose transmembrane transport; mannose transmembrane transport; and sodium ion transport. Predicted to be located in apical plasma membrane. Predicted to be active in plasma membrane. Orthologous to human SLC5A10 (solute carrier family 5 member 10). PHENOTYPE: Mice homozygous for a targeted allele exhibit impaired fructose reabsorption in the kidneys and exacerbated hepatic steatosis induced by fructose. [provided by MGI curators] |