| Primary Identifier | MGI:2137495 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 214384 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables several functions, including R-SMAD binding activity; enzyme binding activity; and transcription coactivator activity. Involved in several processes, including circulatory system development; positive regulation of macromolecule biosynthetic process; and regulation of signal transduction. Acts upstream of or within several processes, including circulatory system development; negative regulation of cardiac muscle cell apoptotic process; and regulation of DNA-templated transcription. Located in chromatin and nucleus. Is expressed in several structures, including cardiovascular system; embryo mesenchyme; genitourinary system; gut; and respiratory system. Used to study congenital megabladder; dilated cardiomyopathy; and patent ductus arteriosus. Human ortholog(s) of this gene implicated in congenital megabladder. Orthologous to human MYOCD (myocardin). PHENOTYPE: Mice homozygous for a null mutation exhibit embryonic lethality and fail to form vascular smooth muscle. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
