| Primary Identifier | MGI:1339713 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 17884 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable actin filament binding activity; double-stranded RNA binding activity; and microfilament motor activity. Acts upstream of or within response to muscle activity. Predicted to be located in myofibril. Predicted to be part of myosin II complex. Predicted to be active in cytoplasm and myosin filament. Is expressed in several structures, including brown fat; heart; limb segment; paraxial mesenchyme; and skeletal musculature. Orthologous to human MYH4 (myosin heavy chain 4). PHENOTYPE: Homozygotes for a targeted null mutation exhibit decreased growth and muscle defects including reduced muscle mass, muscle fiber loss, compensatory fiber hypertrophy, and impaired strength. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
