Primary Identifier | MGI:2136733 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 93896 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable glucagon receptor activity and peptide hormone binding activity. Predicted to be involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway. Predicted to be active in plasma membrane. Is expressed in foregut-midgut junction; hindgut; midgut; and rectum. Orthologous to human GLP2R (glucagon like peptide 2 receptor). PHENOTYPE: Mice homozygous for a null mutation display defects in Paneth cell physiology, increased small bowel bacterial loads, and increased susceptibility to small bowel injury. [provided by MGI curators] |