| Primary Identifier | MGI:2144613 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 104709 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables 1-phosphatidylinositol-3-kinase regulator activity. Contributes to 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity. Involved in G protein-coupled receptor signaling pathway; positive regulation of MAP kinase activity; and positive regulation of T cell differentiation. Located in membrane. Part of phosphatidylinositol 3-kinase complex, class IB. Orthologous to human PIK3R6 (phosphoinositide-3-kinase regulatory subunit 6). PHENOTYPE: Mice homozygous for a knock-out allele exhibit small reductions in lymphocyte and granulocyte and a slight increase in neutrophils. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
