Primary Identifier | MGI:3045254 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 276920 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in spermatid development. Acts upstream of or within acrosome assembly; centrosome cycle; and cilium assembly. Located in several cellular components, including microtubule cytoskeleton; sperm head-tail coupling apparatus; and sperm principal piece. Orthologous to human CCDC42 (coiled-coil domain containing 42). PHENOTYPE: Mice homozygous for a knock-out allele are viable and developmentally normal with no overt behavioral deficits. Males exhibit defects in the number and location of the sperm head-tail coupling apparatus, lack flagellated sperm, and are sterile. [provided by MGI curators] |