| Primary Identifier | MGI:1919173 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 71923 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity. Predicted to be involved in lysosome localization. Predicted to be located in cytoplasmic side of lysosomal membrane. Predicted to be part of BORC complex. Is expressed in several structures, including alimentary system; brain; egg cylinder; genitourinary system; and hemolymphoid system. Orthologous to human BORCS6 (BLOC-1 related complex subunit 6). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased embryo size, small epiblast, egg cylinder degeneration, abnormal primitive streak formation, failure to gastrulate, and complete lethality prior to organogenesis with defects in visceral endoderm and embryo patterning and dysfunction of the endo-lysosomal pathway. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
