Primary Identifier | MGI:1918293 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 108803 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be located in membrane. Orthologous to human SPEM2 (SPEM family member 2). PHENOTYPE: Mice homozygous for a knock-out allele show male sterility, teratozoospermia, oligozoospermia, asthenozoospermia, impaired fertilization, and multiple abnormalities in spermiogenesis, including abnormal acrosome biogenesis, failure of excess cytoplasm shedding, and impaired sperm individualization. [provided by MGI curators] |