Primary Identifier | MGI:88081 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 11889 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables identical protein binding activity. Predicted to be involved in immune response. Predicted to be located in membrane. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including genitourinary system; heart; intestine; liver; and lung. Orthologous to human ASGR1 (asialoglycoprotein receptor 1). PHENOTYPE: Homozygous mutation of this gene results in impaired hepatic clearance of asialoglycoproteins. [provided by MGI curators] |