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Protein Coding Gene : Cxcl16 C-X-C motif chemokine ligand 16

Primary Identifier  MGI:1932682 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  66102
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables chemokine activity; low-density lipoprotein particle receptor activity; and scavenger receptor activity. Involved in T cell chemotaxis and cellular response to lipopolysaccharide. Acts upstream of or within endocytosis. Located in extracellular space and membrane. Is expressed in bladder; female associated reproductive structure; hindbrain meninges; male associated reproductive structure; and spinal cord meninges. Orthologous to human CXCL16 (C-X-C motif chemokine ligand 16).
PHENOTYPE: Mice homozygous for a null allele exhibit decreased NK T cells, decreased secretion and serum levels of IL4 and IFN-gamma, and decreased inhibition of B16 melanoma cell growth by alpha-galactosylceramide treatment. [provided by MGI curators]
  • synonyms:
  • BB024863,
  • C-X-C motif chemokine ligand 16,
  • AV290116,
  • MGI:2144468,
  • Scavenger Receptor,
  • SR-PSOX/CXCL16,
  • MGI:1913352,
  • Cxcl16,
  • expressed sequence AV290116,
  • MGI:2144594,
  • 0910001K24Rik,
  • RIKEN cDNA 0910001K24 gene,
  • SR-PSOX,
  • expressed sequence BB024863

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

8 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For