| Primary Identifier | MGI:892877 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 18806 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables phospholipase D activity. Acts upstream of or within G protein-coupled receptor internalization. Located in brush border membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; nose; and spleen. Orthologous to human PLD2 (phospholipase D2). PHENOTYPE: Mice homozygous for a knock-out fail to exhibit Abeta42 suppression of LTP and show altered brain phosphatidic acid levels. Mice homozygous for a different knock-out allele show normal platelet function, hemostasis and thrombus formation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
