Primary Identifier | MGI:1916973 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 69723 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable metal ion binding activity. Predicted to be involved in protein import into nucleus. Predicted to act upstream of or within DNA metabolic process and response to UV. Predicted to be located in PML body; cytoplasm; and fibrillar center. Predicted to be active in nucleus. Is expressed in several structures, including cerebral cortex ventricular layer; egg cylinder; and oocyte. Orthologous to human RPAIN (RPA interacting protein). PHENOTYPE: Mice homozygous for a knock-out allele show complete embryonic lethality prior to organogenesis. In vitro, blastocysts hatch from the zona pellucida but form outgrowths with few trophectoderm cells. [provided by MGI curators] |