| Primary Identifier | MGI:1194505 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 12261 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables mRNA binding activity and mitochondrial ribosome binding activity. Involved in cytosolic ribosome assembly and positive regulation of mitochondrial translation. Located in mitochondrion. Is expressed in several structures, including brain ventricular layer; genitourinary system; gut; orbito-sphenoid; and tooth. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 33. Orthologous to human C1QBP (complement C1q binding protein). PHENOTYPE: Mice homozygous for a knock-out allele exhibit embryonic lethality by E11.5 with poor development, small embryo size, pale and anemic organs, poor cellular proliferation and impaired mitochondrial electron transport chain function. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
