Primary Identifier | MGI:1891766 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 55984 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable calcium/calmodulin-dependent protein kinase activity and calmodulin binding activity. Predicted to be involved in intracellular signal transduction. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in cytoplasm. Is expressed in central nervous system and retina. Orthologous to human CAMKK1 (calcium/calmodulin dependent protein kinase kinase 1). PHENOTYPE: Mice homozygous for a knock-out allele are viable, fertile and grossly normal but exhibit context fear deficits during both conditioning and long-term follow-up testing. [provided by MGI curators] |