Primary Identifier | MGI:1194498 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 14841 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ATP binding activity; DNA binding activity; and protein kinase activity. Involved in several processes, including chromosome organization involved in meiotic cell cycle; homologous chromosome segregation; and protein phosphorylation. Acts upstream of or within negative regulation of G1/S transition of mitotic cell cycle. Located in male germ cell nucleus. Orthologous to human HASPIN (histone H3 associated protein kinase). PHENOTYPE: Male mice homozygous for a null mutation display disordered germ cells in the testes. [provided by MGI curators] |