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Protein Coding Gene : Haspin histone H3 associated protein kinase

Primary Identifier  MGI:1194498 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  14841
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables ATP binding activity; DNA binding activity; and protein kinase activity. Involved in several processes, including chromosome organization involved in meiotic cell cycle; homologous chromosome segregation; and intracellular signal transduction. Acts upstream of or within negative regulation of G1/S transition of mitotic cell cycle. Located in male germ cell nucleus. Orthologous to human HASPIN (histone H3 associated protein kinase).
PHENOTYPE: Male mice homozygous for a null mutation display disordered germ cells in the testes. [provided by MGI curators]
  • synonyms:
  • histone H3 associated protein kinase,
  • Haspin,
  • Gsg2,
  • germ cell-specific gene 2,
  • germ cell associated 2, haspin

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For