Primary Identifier | MGI:2676888 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 387208 |
Mgi Type | miRNA gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within regulation of dendrite development and regulation of neuron maturation. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to human MIR212 (microRNA 212). PHENOTYPE: Mice homozygous for an allele lacking both Mir212 and Mir132 exhibit disrupted cortical synaptic transmission and plasticity. Mice homozygous for another knock-out allele exhibit abnormal mammary gland development (see Mirc19). [provided by MGI curators] |