Primary Identifier | MGI:2676896 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 387141 |
Mgi Type | miRNA gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within several processes, including cellular response to phenylalanine; long-term synaptic potentiation; and sensory perception of sound. Is expressed in cerebellum and telencephalon. Orthologous to human MIR22 (microRNA 22). PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired cardiac function following treatment with dobutamine or transverse aortic constriction. Another homozygous knock-out allele shows altered cardiac responses to isoproterenol-induced stress. [provided by MGI curators] |