| Primary Identifier | MGI:1100497 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 13447 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables calcium ion binding activity and syntaxin binding activity. Involved in positive regulation of insulin secretion; protein localization; and synaptic vesicle exocytosis. Acts upstream of or within spontaneous neurotransmitter secretion. Located in cytoplasm and plasma membrane. Is expressed in central nervous system; paravertebral ganglion; and retina. Orthologous to human DOC2B (double C2 domain beta). PHENOTYPE: Mice homozygous for a knock-out allele exhibit a reduced frequency of spontaneous neurotransmitter release events with cerebellar Purkinje cells showing continuous spiking without interruption. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
