Primary Identifier | MGI:1923492 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 380714 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable LIM domain binding activity. Involved in glucose homeostasis and positive regulation of insulin secretion. Acts upstream of or within negative regulation of G protein-coupled receptor signaling pathway and regulation of calcium ion-dependent exocytosis. Predicted to be located in secretory granule. Predicted to be active in synapse. Orthologous to human RPH3AL (rabphilin 3A like (without C2 domains)). PHENOTYPE: Mice homozygous for a knock-out allele exhibit disregulation of exocytosis in both endocrine and exocrine cells. [provided by MGI curators] |