Primary Identifier | MGI:1923816 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 76566 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable filamin binding activity. Acts upstream of or within several processes, including actin filament bundle organization; negative regulation of bone mineralization involved in bone maturation; and negative regulation of chondrocyte development. Located in actin filament bundle. Is expressed in several structures, including 1st branchial arch; embryo ectoderm; genital tubercle; lung; and occipital myotome. Orthologous to human RFLNB (refilin B). PHENOTYPE: Mice homozygous for a null allele are viable, fertile, and overtly normal, with no alterations in forebrain and midbrain development, survival, body weight and body length, tibia length or lumbar disk morphology. [provided by MGI curators] |