Primary Identifier | MGI:1913851 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 66601 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables cell-cell adhesion mediator activity and protein homodimerization activity. Involved in cell-cell adhesion. Acts upstream of or within several processes, including brush border assembly; cellular response to hydroperoxide; and intestinal epithelial cell maturation. Is active in cell surface. Orthologous to human TMIGD1 (transmembrane and immunoglobulin domain containing 1). PHENOTYPE: Mice homozygous for a null allele develop intestinal hyperplasia, and polyps in small intestine, large intestine, and rectum. [provided by MGI curators] |