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Protein Coding Gene : Myo18a myosin XVIIIA

Primary Identifier  MGI:2667185 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  360013
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable ADP binding activity; ATP binding activity; and actin filament binding activity. Involved in positive regulation of opsonization and regulation of macrophage activation. Acts upstream of or within cellular response to type II interferon. Located in brush border; cytoskeleton; and phagocytic vesicle. Is expressed in several structures, including gonad; lower leg rest of mesenchyme; molar; musculature; and nervous system. Orthologous to human MYO18A (myosin XVIIIA).
PHENOTYPE: Homozygotes for a null allele exhibit embryonic lethality before E13.5, with abnormal myofibrils in cardiac myocytes. [provided by MGI curators]
  • synonyms:
  • MyoPDZ,
  • myosin XVIIIA,
  • Myo18a

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For