Primary Identifier | MGI:1276558 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 20500 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables sodium:dicarboxylate symporter activity and succinate transmembrane transporter activity. Involved in succinate transmembrane transport. Predicted to be located in apical plasma membrane. Predicted to be active in plasma membrane. Is expressed in 4-cell stage embryo; nervous system; and sensory organ. Orthologous to human SLC13A2 (solute carrier family 13 member 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased Kreb cycle intermediates in the urine but otherwise have normal kidney function and response to ischemia-reperfusion injury and caloric restriction. [provided by MGI curators] |