| Primary Identifier | MGI:2136419 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 237868 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables NAD+ nucleosidase activity. Involved in several processes, including NAD catabolic process; regulation of dendrite morphogenesis; and regulation of synapse pruning. Acts upstream of or within regulation of neuron apoptotic process and response to glucose. Located in several cellular components, including dendrite; microtubule; and mitochondrial outer membrane. Part of protein-containing complex. Is active in cell surface and neuromuscular junction. Is expressed in immune system; nervous system; neural retina; and tongue. Orthologous to human SARM1 (sterile alpha and TIR motif containing 1). PHENOTYPE: Mice homozygous for a null allele exhibit reduced apoptosis induced by oxygen and glucose deprivation in hippocampal slices. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
