Primary Identifier | MGI:1915061 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 67811 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein-macromolecule adaptor activity. Acts upstream of or within mitochondrion organization; negative regulation of macroautophagy; and positive regulation of mitotic cell cycle. Located in mitochondrion. Is expressed in genitourinary system. Orthologous to human POLDIP2 (DNA polymerase delta interacting protein 2). PHENOTYPE: Mice homozygous for a gene trap allele exhibit preweaning lethality and decreased body size. Mice heterozygous for this allele exhibit abnormal induced vasoconstriction and vasodilation with abnormal aorta elastic tissue morphology. [provided by MGI curators] |