Primary Identifier | MGI:107728 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 338367 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including actin filament binding activity; calcium-dependent protein binding activity; and calmodulin binding activity. Predicted to be involved in several processes, including actin filament organization; actin filament-based movement; and early endosome to recycling endosome transport. Located in several cellular components, including brush border; myelin sheath; and neuronal cell body. Is expressed in alimentary system; foot; and sensory organ. Orthologous to human MYO1D (myosin ID). PHENOTYPE: Mice homozygous for a hypomorphic of null allele exhibit increased susceptibility to DSS-induced colitis with increased weight loss and death. [provided by MGI curators] |