| Primary Identifier | MGI:1915138 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 67888 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in positive regulation of endothelial cell differentiation; positive regulation of vasculogenesis; and regulation of sensory perception of pain. Acts upstream of or within several processes, including Notch signaling pathway; circulatory system development; and regulation of intracellular signal transduction. Located in perikaryon; perinuclear region of cytoplasm; and plasma membrane. Is expressed in several structures, including cardiovascular system; eye; genitourinary system; hemolymphoid system gland; and spinal cord. Orthologous to human TMEM100 (transmembrane protein 100). PHENOTYPE: Mice homozygous for a null mutations display prenatal lethality. Mice homozygous for one null mutation display defects in arterial differentiation and maturation and complete lethality during organogenesis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
