| Primary Identifier | MGI:1201678 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 12291 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables low voltage-gated calcium channel activity. Acts upstream of or within several processes, including regulation of atrial cardiac muscle cell membrane depolarization; regulation of heart rate; and response to nickel cation. Located in plasma membrane. Is expressed in central nervous system; heart; hindlimb musculature; lower jaw molar; and retina. Used to study cerebellar ataxia type 42. Human ortholog(s) of this gene implicated in cerebellar ataxia type 42. Orthologous to human CACNA1G (calcium voltage-gated channel subunit alpha1 G). PHENOTYPE: Homozygote null mice display disrupted sleeping patterns, altered amounts of activity, abnormal action potentials in the brain, prolonged electrical conductance in the heart, and resistance to diet-induced obesity. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
